diff --git a/src/app/accessibility/accessibility-settings.service.spec.ts b/src/app/accessibility/accessibility-settings.service.spec.ts
index 26cf488450..2132ff090e 100644
--- a/src/app/accessibility/accessibility-settings.service.spec.ts
+++ b/src/app/accessibility/accessibility-settings.service.spec.ts
@@ -17,7 +17,6 @@ import { AuthServiceStub } from '../shared/testing/auth-service.stub';
 import {
   ACCESSIBILITY_COOKIE,
   ACCESSIBILITY_SETTINGS_METADATA_KEY,
-  AccessibilitySetting,
   AccessibilitySettings,
   AccessibilitySettingsService,
 } from './accessibility-settings.service';
@@ -48,17 +47,6 @@ describe('accessibilitySettingsService', () => {
     );
   });
 
-  describe('getALlAccessibilitySettingsKeys', () => {
-    it('should return an array containing all accessibility setting names', () => {
-      const settingNames: AccessibilitySetting[] = [
-        AccessibilitySetting.NotificationTimeOut,
-        AccessibilitySetting.LiveRegionTimeOut,
-      ];
-
-      expect(service.getAllAccessibilitySettingKeys()).toEqual(settingNames);
-    });
-  });
-
   describe('get', () => {
     it('should return the setting if it is set', () => {
       const settings: AccessibilitySettings = {
@@ -67,7 +55,7 @@ describe('accessibilitySettingsService', () => {
 
       service.getAll = jasmine.createSpy('getAll').and.returnValue(of(settings));
 
-      service.get(AccessibilitySetting.NotificationTimeOut, 'default').subscribe(value =>
+      service.get('notificationTimeOut', 'default').subscribe(value =>
         expect(value).toEqual('1000'),
       );
     });
@@ -79,7 +67,7 @@ describe('accessibilitySettingsService', () => {
 
       service.getAll = jasmine.createSpy('getAll').and.returnValue(of(settings));
 
-      service.get(AccessibilitySetting.LiveRegionTimeOut, 'default').subscribe(value =>
+      service.get('liveRegionTimeOut', 'default').subscribe(value =>
         expect(value).toEqual('default'),
       );
     });
@@ -89,7 +77,7 @@ describe('accessibilitySettingsService', () => {
     it('should return the setting as number if the value for the setting can be parsed to a number', () => {
       service.get = jasmine.createSpy('get').and.returnValue(of('1000'));
 
-      service.getAsNumber(AccessibilitySetting.NotificationTimeOut).subscribe(value =>
+      service.getAsNumber('notificationTimeOut').subscribe(value =>
         expect(value).toEqual(1000),
       );
     });
@@ -97,7 +85,7 @@ describe('accessibilitySettingsService', () => {
     it('should return the default value if no value is set for the setting', () => {
       service.get = jasmine.createSpy('get').and.returnValue(of(null));
 
-      service.getAsNumber(AccessibilitySetting.NotificationTimeOut, 123).subscribe(value =>
+      service.getAsNumber('notificationTimeOut', 123).subscribe(value =>
         expect(value).toEqual(123),
       );
     });
@@ -105,7 +93,7 @@ describe('accessibilitySettingsService', () => {
     it('should return the default value if the value for the setting can not be parsed to a number', () => {
       service.get = jasmine.createSpy('get').and.returnValue(of('text'));
 
-      service.getAsNumber(AccessibilitySetting.NotificationTimeOut, 123).subscribe(value =>
+      service.getAsNumber('notificationTimeOut', 123).subscribe(value =>
         expect(value).toEqual(123),
       );
     });
@@ -183,7 +171,7 @@ describe('accessibilitySettingsService', () => {
     it('should correctly update the chosen setting', () => {
       service.updateSettings = jasmine.createSpy('updateSettings');
 
-      service.set(AccessibilitySetting.LiveRegionTimeOut, '500');
+      service.set('liveRegionTimeOut', '500');
       expect(service.updateSettings).toHaveBeenCalledWith({ liveRegionTimeOut: '500' });
     });
   });
@@ -314,7 +302,7 @@ describe('accessibilitySettingsService', () => {
     });
 
     it('should set the settings in metadata', () => {
-      service.setSettingsInMetadata(ePerson, { [AccessibilitySetting.LiveRegionTimeOut]: '500' }).subscribe();
+      service.setSettingsInMetadata(ePerson, { ['liveRegionTimeOut']: '500' }).subscribe();
       expect(ePerson.setMetadata).toHaveBeenCalled();
     });
 
@@ -325,19 +313,19 @@ describe('accessibilitySettingsService', () => {
     });
 
     it('should create a patch with the metadata changes', () => {
-      service.setSettingsInMetadata(ePerson, { [AccessibilitySetting.LiveRegionTimeOut]: '500' }).subscribe();
+      service.setSettingsInMetadata(ePerson, { ['liveRegionTimeOut']: '500' }).subscribe();
       expect(ePersonService.createPatchFromCache).toHaveBeenCalled();
     });
 
     it('should send the patch request', () => {
-      service.setSettingsInMetadata(ePerson, { [AccessibilitySetting.LiveRegionTimeOut]: '500' }).subscribe();
+      service.setSettingsInMetadata(ePerson, { ['liveRegionTimeOut']: '500' }).subscribe();
       expect(ePersonService.patch).toHaveBeenCalled();
     });
 
     it('should emit true when the update succeeded', fakeAsync(() => {
       ePersonService.patch = jasmine.createSpy().and.returnValue(createSuccessfulRemoteDataObject$({}));
 
-      service.setSettingsInMetadata(ePerson, { [AccessibilitySetting.LiveRegionTimeOut]: '500' })
+      service.setSettingsInMetadata(ePerson, { ['liveRegionTimeOut']: '500' })
         .subscribe(value => {
           expect(value).toBeTrue();
         });
@@ -348,7 +336,7 @@ describe('accessibilitySettingsService', () => {
     it('should emit false when the update failed', fakeAsync(() => {
       ePersonService.patch = jasmine.createSpy().and.returnValue(createFailedRemoteDataObject$());
 
-      service.setSettingsInMetadata(ePerson, { [AccessibilitySetting.LiveRegionTimeOut]: '500' })
+      service.setSettingsInMetadata(ePerson, { ['liveRegionTimeOut']: '500' })
         .subscribe(value => {
           expect(value).toBeFalse();
         });
@@ -364,7 +352,7 @@ describe('accessibilitySettingsService', () => {
     });
 
     it('should store the settings in a cookie', () => {
-      service.setSettingsInCookie({ [AccessibilitySetting.LiveRegionTimeOut]: '500' });
+      service.setSettingsInCookie({ ['liveRegionTimeOut']: '500' });
       expect(cookieService.set).toHaveBeenCalled();
     });
 
@@ -375,12 +363,4 @@ describe('accessibilitySettingsService', () => {
     });
   });
 
-  describe('getInputType', () => {
-    it('should correctly return the input type', () => {
-      expect(service.getInputType(AccessibilitySetting.NotificationTimeOut)).toEqual('number');
-      expect(service.getInputType(AccessibilitySetting.LiveRegionTimeOut)).toEqual('number');
-      expect(service.getInputType('unknownValue' as AccessibilitySetting)).toEqual('text');
-    });
-  });
-
 });
diff --git a/src/app/accessibility/accessibility-settings.service.stub.ts b/src/app/accessibility/accessibility-settings.service.stub.ts
index b3fc40d1b3..103b1805dc 100644
--- a/src/app/accessibility/accessibility-settings.service.stub.ts
+++ b/src/app/accessibility/accessibility-settings.service.stub.ts
@@ -32,4 +32,10 @@ export class AccessibilitySettingsServiceStub {
   setSettingsInCookie = jasmine.createSpy('setSettingsInCookie');
 
   getInputType = jasmine.createSpy('getInputType').and.returnValue('text');
+
+  convertFormValuesToStoredValues = jasmine.createSpy('convertFormValuesToStoredValues').and.returnValue({});
+
+  convertStoredValuesToFormValues = jasmine.createSpy('convertStoredValuesToFormValues').and.returnValue({});
+
+  getPlaceholder = jasmine.createSpy('getPlaceholder').and.returnValue('placeholder');
 }
diff --git a/src/app/accessibility/accessibility-settings.service.ts b/src/app/accessibility/accessibility-settings.service.ts
index 6ff19be9bb..808c5ea2b2 100644
--- a/src/app/accessibility/accessibility-settings.service.ts
+++ b/src/app/accessibility/accessibility-settings.service.ts
@@ -19,8 +19,8 @@ import { getFirstCompletedRemoteData } from '../core/shared/operators';
 import {
   hasValue,
   isNotEmpty,
-  isNotEmptyOperator,
 } from '../shared/empty.util';
+import { createSuccessfulRemoteDataObject$ } from '../shared/remote-data.utils';
 
 /**
  * Name of the cookie used to store the settings locally
@@ -33,16 +33,30 @@ export const ACCESSIBILITY_COOKIE = 'dsAccessibilityCookie';
 export const ACCESSIBILITY_SETTINGS_METADATA_KEY = 'dspace.accessibility.settings';
 
 /**
- * Enum containing all possible accessibility settings.
- * When adding new settings, the {@link AccessibilitySettingsService#getInputType} method and the i18n keys for the
- * accessibility settings page should be updated.
+ * Type containing all possible accessibility settings.
+ * When adding new settings, make sure to add the new setting to the accessibility-settings component form.
+ * The converter methods to convert from stored format to form format (and vice-versa) need to be updated as well.
  */
-export enum AccessibilitySetting {
-  NotificationTimeOut = 'notificationTimeOut',
-  LiveRegionTimeOut = 'liveRegionTimeOut',
-}
+export type AccessibilitySetting = 'notificationTimeOut' | 'liveRegionTimeOut';
 
-export type AccessibilitySettings = { [key in AccessibilitySetting]?: any };
+/**
+ * Type representing an object that contains accessibility settings values for all accessibility settings.
+ */
+export type FullAccessibilitySettings = { [key in AccessibilitySetting]: string };
+
+/**
+ * Type representing an object that contains accessibility settings values for some accessibility settings.
+ */
+export type AccessibilitySettings = Partial<FullAccessibilitySettings>;
+
+/**
+ * The accessibility settings object format used by the accessibility-settings component form.
+ */
+export interface AccessibilitySettingsFormValues {
+  notificationTimeOutEnabled: boolean,
+  notificationTimeOut: string,
+  liveRegionTimeOut: string,
+}
 
 /**
  * Service handling the retrieval and configuration of accessibility settings.
@@ -62,10 +76,6 @@ export class AccessibilitySettingsService {
   ) {
   }
 
-  getAllAccessibilitySettingKeys(): AccessibilitySetting[] {
-    return Object.entries(AccessibilitySetting).map(([_, val]) => val);
-  }
-
   /**
    * Get the stored value for the provided {@link AccessibilitySetting}. If the value does not exist or if it is empty,
    * the provided defaultValue is emitted instead.
@@ -204,8 +214,8 @@ export class AccessibilitySettingsService {
 
     return this.ePersonService.createPatchFromCache(user).pipe(
       take(1),
-      isNotEmptyOperator(),
-      switchMap(operations => this.ePersonService.patch(user, operations)),
+      switchMap(operations =>
+        isNotEmpty(operations) ? this.ePersonService.patch(user, operations) : createSuccessfulRemoteDataObject$({})),
       getFirstCompletedRemoteData(),
       map(rd => rd.hasSucceeded),
     );
@@ -223,17 +233,75 @@ export class AccessibilitySettingsService {
   }
 
   /**
-   * Returns the input type that a form should use for the provided {@link AccessibilitySetting}
+   * Clears all settings in the cookie and attempts to clear settings in metadata.
+   * Emits true if settings in metadata were cleared and false otherwise.
    */
-  getInputType(setting: AccessibilitySetting): string {
+  clearSettings(): Observable<boolean> {
+    this.setSettingsInCookie({});
+    return this.setSettingsInAuthenticatedUserMetadata({});
+  }
+
+  /**
+   * Retrieve the placeholder to be used for the provided AccessibilitySetting.
+   * Returns an empty string when no placeholder is specified for the provided setting.
+   */
+  getPlaceholder(setting: AccessibilitySetting): string {
     switch (setting) {
-      case AccessibilitySetting.NotificationTimeOut:
-        return 'number';
-      case AccessibilitySetting.LiveRegionTimeOut:
-        return 'number';
+      case 'notificationTimeOut':
+        return millisecondsToSeconds(environment.notifications.timeOut.toString());
+      case 'liveRegionTimeOut':
+        return millisecondsToSeconds(environment.liveRegion.messageTimeOutDurationMs.toString());
       default:
-        return 'text';
+        return '';
     }
   }
 
+  /**
+   * Convert values in the provided accessibility settings object to values ready to be stored.
+   */
+  convertFormValuesToStoredValues(settings: AccessibilitySettingsFormValues): FullAccessibilitySettings {
+    return {
+      notificationTimeOut: settings.notificationTimeOutEnabled ?
+        secondsToMilliseconds(settings.notificationTimeOut) : '0',
+      liveRegionTimeOut: secondsToMilliseconds(settings.liveRegionTimeOut),
+    };
+  }
+
+  /**
+   * Convert values in the provided accessibility settings object to values ready to show in the form.
+   */
+  convertStoredValuesToFormValues(settings: AccessibilitySettings): AccessibilitySettingsFormValues {
+    return {
+      notificationTimeOutEnabled: parseFloat(settings.notificationTimeOut) !== 0,
+      notificationTimeOut: millisecondsToSeconds(settings.notificationTimeOut),
+      liveRegionTimeOut: millisecondsToSeconds(settings.liveRegionTimeOut),
+    };
+  }
+
+}
+
+/**
+ * Converts a string representing seconds to a string representing milliseconds
+ * Returns null if the input could not be parsed to a float
+ */
+function secondsToMilliseconds(secondsStr: string): string {
+  const seconds = parseFloat(secondsStr);
+  if (isNaN(seconds)) {
+    return null;
+  } else {
+    return (seconds * 1000).toString();
+  }
+}
+
+/**
+ * Converts a string representing milliseconds to a string representing seconds
+ * Returns null if the input could not be parsed to a float
+ */
+function millisecondsToSeconds(millisecondsStr: string): string {
+  const milliseconds = parseFloat(millisecondsStr);
+  if (isNaN(milliseconds)) {
+    return null;
+  } else {
+    return (milliseconds / 1000).toString();
+  }
 }
diff --git a/src/app/info/accessibility-settings/accessibility-settings.component.html b/src/app/info/accessibility-settings/accessibility-settings.component.html
index 6550c6a288..cacfae61fc 100644
--- a/src/app/info/accessibility-settings/accessibility-settings.component.html
+++ b/src/app/info/accessibility-settings/accessibility-settings.component.html
@@ -2,25 +2,87 @@
   <h2>{{ 'info.accessibility-settings.title' | translate }}</h2>
 
   <form>
-    <div *ngFor="let setting of accessibilitySettingsOptions" class="form-group row">
-      <label [for]="setting + 'Input'" class="col-sm-2 col-form-label">
-        {{ 'info.accessibility-settings.' + setting + '.label' | translate }}
+    <div class="form-group row">
+      <label [for]="'disableNotificationTimeOutInput'" class="col-sm-2 col-form-label">
+        {{ 'info.accessibility-settings.disableNotificationTimeOut.label' | translate }}
       </label>
 
-      <div class="col-sm-10">
-        <input [type]="getInputType(setting)" [id]="setting + 'Input'" class="form-control"
-               [(ngModel)]="formValues[setting]" [ngModelOptions]="{ standalone: true }"
-               [attr.aria-describedby]="setting + 'Hint'">
+      <div class="col-sm-5">
+        <ui-switch [id]="'disableNotificationTimeOutInput'"
+                   [(ngModel)]="formValues.notificationTimeOutEnabled"
+                   [ngModelOptions]="{ standalone: true }"
+        ></ui-switch>
+      </div>
 
-        <small [id]="setting + 'Hint'" class="form-text text-muted">
-          {{ 'info.accessibility-settings.' + setting + '.hint' | translate }}
-        </small>
+      <div class="col-sm-1" *dsContextHelp="{
+            content: 'info.accessibility-settings.disableNotificationTimeOut.hint',
+            id: 'disableNotificationTimeOutHelp',
+            iconPlacement: 'right',
+            tooltipPlacement: 'right'
+          }">
       </div>
     </div>
 
-    <button type="submit" (click)="saveSettings()" class="btn btn-primary">
-      {{ 'info.accessibility-settings.submit' | translate }}
-    </button>
+    <div class="form-group row">
+      <label [for]="'notificationTimeOutInput'" class="col-sm-2 col-form-label">
+        {{ 'info.accessibility-settings.notificationTimeOut.label' | translate }}
+      </label>
+
+      <div class="col-sm-4">
+        <input [type]="'number'" [id]="'notificationTimeOutInput'" class="form-control"
+               [placeholder]="getPlaceholder('notificationTimeOut')"
+               [readOnly]="!formValues.notificationTimeOutEnabled"
+               [(ngModel)]="formValues.notificationTimeOut" [ngModelOptions]="{ standalone: true }"
+               [attr.aria-describedby]="'notificationTimeOutHint'">
+      </div>
+
+      <div class="col-sm-1 col-form-label">
+        {{ 'info.accessibility-settings.notificationTimeOut.unit' | translate }}
+      </div>
+
+      <div class="col-sm-1" *dsContextHelp="{
+            content: 'info.accessibility-settings.notificationTimeOut.hint',
+            id: 'notificationTimeOutHelp',
+            iconPlacement: 'right',
+            tooltipPlacement: 'right'
+          }">
+      </div>
+    </div>
+
+    <div class="form-group row">
+      <label [for]="'liveRegionTimeOutInput'" class="col-sm-2 col-form-label">
+        {{ 'info.accessibility-settings.liveRegionTimeOut.label' | translate }}
+      </label>
+
+      <div class="col-sm-4">
+        <input [type]="'number'" [id]="'liveRegionTimeOutInput'" class="form-control"
+               [placeholder]="getPlaceholder('liveRegionTimeOut')"
+               [(ngModel)]="formValues.liveRegionTimeOut" [ngModelOptions]="{ standalone: true }"
+               [attr.aria-describedby]="'liveRegionTimeOutHint'">
+      </div>
+
+      <div class="col-sm-1 col-form-label">
+        {{ 'info.accessibility-settings.liveRegionTimeOut.unit' | translate }}
+      </div>
+
+      <div class="col-sm-1" *dsContextHelp="{
+            content: 'info.accessibility-settings.liveRegionTimeOut.hint',
+            id: 'liveRegionTimeOutHelp',
+            iconPlacement: 'right',
+            tooltipPlacement: 'right'
+          }">
+      </div>
+    </div>
+
+    <div role="group">
+      <button type="submit" (click)="saveSettings()" class="btn btn-primary mr-2">
+        {{ 'info.accessibility-settings.submit' | translate }}
+      </button>
+      <button type="reset" (click)="resetSettings()" class="btn btn-warning">
+        {{ 'info.accessibility-settings.reset' | translate }}
+      </button>
+    </div>
+
   </form>
 
 </div>
diff --git a/src/app/info/accessibility-settings/accessibility-settings.component.spec.ts b/src/app/info/accessibility-settings/accessibility-settings.component.spec.ts
index 10147960d6..148a02d77a 100644
--- a/src/app/info/accessibility-settings/accessibility-settings.component.spec.ts
+++ b/src/app/info/accessibility-settings/accessibility-settings.component.spec.ts
@@ -6,11 +6,9 @@ import {
 } from '@angular/core/testing';
 import { TranslateModule } from '@ngx-translate/core';
 import { of } from 'rxjs';
+import { ContextHelpDirective } from 'src/app/shared/context-help.directive';
 
-import {
-  AccessibilitySetting,
-  AccessibilitySettingsService,
-} from '../../accessibility/accessibility-settings.service';
+import { AccessibilitySettingsService } from '../../accessibility/accessibility-settings.service';
 import { getAccessibilitySettingsServiceStub } from '../../accessibility/accessibility-settings.service.stub';
 import { AuthService } from '../../core/auth/auth.service';
 import { NotificationsService } from '../../shared/notifications/notifications.service';
@@ -40,6 +38,10 @@ describe('AccessibilitySettingsComponent', () => {
         { provide: NotificationsService, useValue: notificationsService },
       ],
       schemas: [NO_ERRORS_SCHEMA],
+    }).overrideComponent(AccessibilitySettingsComponent, {
+      remove: {
+        imports: [ContextHelpDirective],
+      },
     }).compileComponents();
   }));
 
@@ -54,19 +56,12 @@ describe('AccessibilitySettingsComponent', () => {
   });
 
   describe('On Init', () => {
-    it('should retrieve all accessibility settings options', () => {
-      expect(settingsService.getAllAccessibilitySettingKeys).toHaveBeenCalled();
-    });
-
     it('should retrieve the current settings', () => {
       expect(settingsService.getAll).toHaveBeenCalled();
     });
-  });
 
-  describe('getInputType', () => {
-    it('should retrieve the input type for the setting from the service', () => {
-      component.getInputType(AccessibilitySetting.LiveRegionTimeOut);
-      expect(settingsService.getInputType).toHaveBeenCalledWith(AccessibilitySetting.LiveRegionTimeOut);
+    it('should convert retrieved settings to form format', () => {
+      expect(settingsService.convertStoredValuesToFormValues).toHaveBeenCalled();
     });
   });
 
@@ -77,6 +72,12 @@ describe('AccessibilitySettingsComponent', () => {
       expect(settingsService.setSettings).toHaveBeenCalled();
     });
 
+    it('should convert form settings to stored format', () => {
+      settingsService.setSettings = jasmine.createSpy('setSettings').and.returnValue(of('cookie'));
+      component.saveSettings();
+      expect(settingsService.convertFormValuesToStoredValues).toHaveBeenCalled();
+    });
+
     it('should give the user a notification mentioning where the settings were saved', () => {
       settingsService.setSettings = jasmine.createSpy('setSettings').and.returnValue(of('cookie'));
       component.saveSettings();
diff --git a/src/app/info/accessibility-settings/accessibility-settings.component.ts b/src/app/info/accessibility-settings/accessibility-settings.component.ts
index dca94c67c1..47b80b44c1 100644
--- a/src/app/info/accessibility-settings/accessibility-settings.component.ts
+++ b/src/app/info/accessibility-settings/accessibility-settings.component.ts
@@ -8,16 +8,21 @@ import {
   TranslateModule,
   TranslateService,
 } from '@ngx-translate/core';
+import { UiSwitchModule } from 'ngx-ui-switch';
 import { take } from 'rxjs';
 
 import {
   AccessibilitySetting,
-  AccessibilitySettings,
+  AccessibilitySettingsFormValues,
   AccessibilitySettingsService,
 } from '../../accessibility/accessibility-settings.service';
 import { AuthService } from '../../core/auth/auth.service';
+import { ContextHelpDirective } from '../../shared/context-help.directive';
 import { NotificationsService } from '../../shared/notifications/notifications.service';
 
+/**
+ * Component providing the form where users can update accessibility settings.
+ */
 @Component({
   selector: 'ds-accessibility-settings',
   templateUrl: './accessibility-settings.component.html',
@@ -25,14 +30,14 @@ import { NotificationsService } from '../../shared/notifications/notifications.s
     CommonModule,
     TranslateModule,
     FormsModule,
+    UiSwitchModule,
+    ContextHelpDirective,
   ],
   standalone: true,
 })
 export class AccessibilitySettingsComponent implements OnInit {
 
-  protected accessibilitySettingsOptions: AccessibilitySetting[];
-
-  protected formValues: AccessibilitySettings = { };
+  protected formValues: AccessibilitySettingsFormValues;
 
   constructor(
     protected authService: AuthService,
@@ -43,19 +48,41 @@ export class AccessibilitySettingsComponent implements OnInit {
   }
 
   ngOnInit() {
-    this.accessibilitySettingsOptions = this.settingsService.getAllAccessibilitySettingKeys();
-    this.settingsService.getAll().pipe(take(1)).subscribe(currentSettings => {
-      this.formValues = currentSettings;
+    this.updateFormValues();
+  }
+
+  getPlaceholder(setting: AccessibilitySetting): string {
+    return this.settingsService.getPlaceholder(setting);
+  }
+
+  /**
+   * Saves the user-configured settings
+   */
+  saveSettings() {
+    const formValues = this.formValues;
+    const convertedValues = this.settingsService.convertFormValuesToStoredValues(formValues);
+    this.settingsService.setSettings(convertedValues).pipe(take(1)).subscribe(location => {
+      this.notificationsService.success(null, this.translateService.instant('info.accessibility-settings.save-notification.' + location));
+      this.updateFormValues();
     });
   }
 
-  getInputType(setting: AccessibilitySetting): string {
-    return this.settingsService.getInputType(setting);
+  /**
+   * Updates the form values with the currently stored accessibility settings
+   */
+  updateFormValues() {
+    this.settingsService.getAll().pipe(take(1)).subscribe(storedSettings => {
+      this.formValues = this.settingsService.convertStoredValuesToFormValues(storedSettings);
+    });
   }
 
-  saveSettings() {
-    this.settingsService.setSettings(this.formValues).pipe(take(1)).subscribe(location => {
-      this.notificationsService.success(null, this.translateService.instant('info.accessibility-settings.save-notification.' + location));
+  /**
+   * Resets accessibility settings
+   */
+  resetSettings() {
+    this.settingsService.clearSettings().pipe(take(1)).subscribe(() => {
+      this.notificationsService.success(null, this.translateService.instant('info.accessibility-settings.reset-notification'));
+      this.updateFormValues();
     });
   }
 
diff --git a/src/app/profile-page/profile-page.component.html b/src/app/profile-page/profile-page.component.html
index 6b0dd8e6d6..fe91cf73d7 100644
--- a/src/app/profile-page/profile-page.component.html
+++ b/src/app/profile-page/profile-page.component.html
@@ -36,7 +36,7 @@
     <div class="card mb-4">
       <div class="card-header">{{'profile.card.accessibility.header' | translate}}</div>
       <div class="card-body">
-        <div class="mb-1">{{'profile.card.accessibility.content' | translate}}</div>
+        <ds-alert class="mb-4" [type]="'alert-info'">{{'profile.card.accessibility.content' | translate}}</ds-alert>
         <a [routerLink]="'/info/accessibility'">{{'profile.card.accessibility.link' | translate}}</a>
       </div>
     </div>
diff --git a/src/app/profile-page/profile-page.component.spec.ts b/src/app/profile-page/profile-page.component.spec.ts
index 810cf63389..47c9151b47 100644
--- a/src/app/profile-page/profile-page.component.spec.ts
+++ b/src/app/profile-page/profile-page.component.spec.ts
@@ -5,6 +5,7 @@ import {
   waitForAsync,
 } from '@angular/core/testing';
 import { By } from '@angular/platform-browser';
+import { NoopAnimationsModule } from '@angular/platform-browser/animations';
 import { RouterModule } from '@angular/router';
 import { StoreModule } from '@ngrx/store';
 import { provideMockStore } from '@ngrx/store/testing';
@@ -116,6 +117,7 @@ describe('ProfilePageComponent', () => {
         RouterModule.forRoot([]),
         ProfilePageComponent,
         VarDirective,
+        NoopAnimationsModule,
       ],
       providers: [
         { provide: EPersonDataService, useValue: epersonService },
diff --git a/src/app/profile-page/profile-page.component.ts b/src/app/profile-page/profile-page.component.ts
index 673b985698..2e27fc43bb 100644
--- a/src/app/profile-page/profile-page.component.ts
+++ b/src/app/profile-page/profile-page.component.ts
@@ -41,6 +41,7 @@ import {
   getRemoteDataPayload,
 } from '../core/shared/operators';
 import { SuggestionsNotificationComponent } from '../notifications/suggestions-notification/suggestions-notification.component';
+import { AlertComponent } from '../shared/alert/alert.component';
 import {
   hasValue,
   isNotEmpty,
@@ -67,6 +68,7 @@ import { ProfilePageSecurityFormComponent } from './profile-page-security-form/p
     NgForOf,
     SuggestionsNotificationComponent,
     RouterModule,
+    AlertComponent,
   ],
   standalone: true,
 })
diff --git a/src/app/shared/live-region/live-region.service.ts b/src/app/shared/live-region/live-region.service.ts
index c1b889be04..c972867dbc 100644
--- a/src/app/shared/live-region/live-region.service.ts
+++ b/src/app/shared/live-region/live-region.service.ts
@@ -9,10 +9,7 @@ import {
 } from 'rxjs';
 
 import { environment } from '../../../environments/environment';
-import {
-  AccessibilitySetting,
-  AccessibilitySettingsService,
-} from '../../accessibility/accessibility-settings.service';
+import { AccessibilitySettingsService } from '../../accessibility/accessibility-settings.service';
 import { UUIDService } from '../../core/shared/uuid.service';
 
 export const MIN_MESSAGE_DURATION = 200;
@@ -141,7 +138,7 @@ export class LiveRegionService {
    */
   getConfiguredMessageTimeOutMs(): Observable<number> {
     return this.accessibilitySettingsService.getAsNumber(
-      AccessibilitySetting.LiveRegionTimeOut,
+      'liveRegionTimeOut',
       this.getMessageTimeOutMs(),
     ).pipe(map(timeOut => Math.max(timeOut, MIN_MESSAGE_DURATION)));
   }
diff --git a/src/app/shared/notifications/notifications-board/notifications-board.component.ts b/src/app/shared/notifications/notifications-board/notifications-board.component.ts
index fdb6d2240e..44cdf72786 100644
--- a/src/app/shared/notifications/notifications-board/notifications-board.component.ts
+++ b/src/app/shared/notifications/notifications-board/notifications-board.component.ts
@@ -16,7 +16,7 @@ import {
   Store,
 } from '@ngrx/store';
 import cloneDeep from 'lodash/cloneDeep';
-import difference from 'lodash/difference';
+import differenceWith from 'lodash/differenceWith';
 import {
   BehaviorSubject,
   Subscription,
@@ -24,10 +24,7 @@ import {
 } from 'rxjs';
 
 import { INotificationBoardOptions } from '../../../../config/notifications-config.interfaces';
-import {
-  AccessibilitySetting,
-  AccessibilitySettingsService,
-} from '../../../accessibility/accessibility-settings.service';
+import { AccessibilitySettingsService } from '../../../accessibility/accessibility-settings.service';
 import { AppState } from '../../../app.reducer';
 import { INotification } from '../models/notification.model';
 import { NotificationComponent } from '../notification/notification.component';
@@ -82,13 +79,13 @@ export class NotificationsBoardComponent implements OnInit, OnDestroy {
           this.notifications = [];
         } else if (state.length > this.notifications.length) {
           // Add
-          const newElem = difference(state, this.notifications);
+          const newElem = differenceWith(state, this.notifications, this.byId);
           newElem.forEach((notification) => {
             this.add(notification);
           });
         } else {
           // Remove
-          const delElem = difference(this.notifications, state);
+          const delElem = differenceWith(this.notifications, state, this.byId);
           delElem.forEach((notification) => {
             this.notifications = this.notifications.filter((item: INotification) => item.id !== notification.id);
 
@@ -98,6 +95,9 @@ export class NotificationsBoardComponent implements OnInit, OnDestroy {
       });
   }
 
+  private byId = (notificationA: INotification, notificationB: INotification) =>
+    notificationA.id === notificationB.id;
+
   // Add the new notification to the notification array
   add(item: INotification): void {
     const toBlock: boolean = this.block(item);
@@ -108,7 +108,7 @@ export class NotificationsBoardComponent implements OnInit, OnDestroy {
 
       // It would be a bit better to handle the retrieval of configured settings in the NotificationsService.
       // Due to circular dependencies this is difficult to implement.
-      this.accessibilitySettingsService.getAsNumber(AccessibilitySetting.NotificationTimeOut, item.options.timeOut)
+      this.accessibilitySettingsService.getAsNumber('notificationTimeOut', item.options.timeOut)
         .pipe(take(1)).subscribe(timeOut => {
           if (timeOut < 0) {
             timeOut = 0;
diff --git a/src/assets/i18n/en.json5 b/src/assets/i18n/en.json5
index 54a4803207..0f50a131fa 100644
--- a/src/assets/i18n/en.json5
+++ b/src/assets/i18n/en.json5
@@ -2132,18 +2132,30 @@
 
   "info.accessibility-settings.breadcrumbs": "Accessibility settings",
 
+  "info.accessibility-settings.disableNotificationTimeOut.label": "Hide notifications automatically",
+
+  "info.accessibility-settings.disableNotificationTimeOut.hint": "When this toggle is activated, notifications will remain until manually closed.",
+
   "info.accessibility-settings.liveRegionTimeOut.label": "Live region time-out",
 
-  "info.accessibility-settings.liveRegionTimeOut.hint": "The duration in milliseconds after which a message in the live region disappears.",
+  "info.accessibility-settings.liveRegionTimeOut.hint": "The duration after which a message in the live region disappears.",
+
+  "info.accessibility-settings.liveRegionTimeOut.unit": "Seconds",
 
   "info.accessibility-settings.notificationTimeOut.label": "Notification time-out",
 
-  "info.accessibility-settings.notificationTimeOut.hint": "The duration in milliseconds after which a notification disappears. Set to 0 for notifications to remain indefinitely.",
+  "info.accessibility-settings.notificationTimeOut.hint": "The duration after which a notification disappears.",
+
+  "info.accessibility-settings.notificationTimeOut.unit": "Seconds",
 
   "info.accessibility-settings.save-notification.cookie": "Successfully saved settings locally.",
 
   "info.accessibility-settings.save-notification.metadata": "Successfully saved settings on the user profile.",
 
+  "info.accessibility-settings.reset-notification": "Successfully reset settings.",
+
+  "info.accessibility-settings.reset": "Reset accessibility settings",
+
   "info.accessibility-settings.submit": "Save accessibility settings",
 
   "info.accessibility-settings.title": "Accessibility settings",
@@ -3894,7 +3906,7 @@
 
   "profile.card.accessibility.header": "Accessibility",
 
-  "profile.card.accessibility.link": "Accessibility Settings Page",
+  "profile.card.accessibility.link": "Go to Accessibility Settings Page",
 
   "profile.card.identify": "Identify",
 
diff --git a/src/themes/custom/app/profile-page/profile-page.component.ts b/src/themes/custom/app/profile-page/profile-page.component.ts
index 687cf9bc9d..4b9250d48c 100644
--- a/src/themes/custom/app/profile-page/profile-page.component.ts
+++ b/src/themes/custom/app/profile-page/profile-page.component.ts
@@ -12,6 +12,7 @@ import { ProfilePageComponent as BaseComponent } from '../../../../app/profile-p
 import { ThemedProfilePageMetadataFormComponent } from '../../../../app/profile-page/profile-page-metadata-form/themed-profile-page-metadata-form.component';
 import { ProfilePageResearcherFormComponent } from '../../../../app/profile-page/profile-page-researcher-form/profile-page-researcher-form.component';
 import { ProfilePageSecurityFormComponent } from '../../../../app/profile-page/profile-page-security-form/profile-page-security-form.component';
+import { AlertComponent } from '../../../../app/shared/alert/alert.component';
 import { VarDirective } from '../../../../app/shared/utils/var.directive';
 
 @Component({
@@ -32,6 +33,7 @@ import { VarDirective } from '../../../../app/shared/utils/var.directive';
     NgForOf,
     SuggestionsNotificationComponent,
     RouterModule,
+    AlertComponent,
   ],
 })
 /**